JAK-2 Mutation (27M)

2022.01.25 19:31 careermove12 JAK-2 Mutation (27M)

Hello, I was recently diagnosed with Essential Thrombocytosis (an MPN) having a JAK-2 mutation with an allele burden of ~4.3%. Can anyone explain in layman’s terms what the allele burden means and it’s significance? As most people diagnosed with Essential Thrombocytosis are in their 50s and 60s, I can’t help but feel lost, confused, and wondering where I went wrong (and if there was anything I could have done to prevent this). Additionally, can anyone let me know what my prognosis might look like?
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2022.01.25 19:31 picinthepic What is your sexual fantasy?

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2022.01.25 19:31 aFineMoose What Plot Hole Could Have Easily Been Solved with One or Two Lines?

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2022.01.25 19:31 painttheforest Intermittent fasting on lithium carbonate

I’m on 900 mg (450 x 2) + Zoloft 100 mg
I’ve been water fasting between 16/8 and 20/4 a day over the last two weeks, trying to shift some of this lithium weight. But the fatigue and disorientation is high. All the time, not just when I’m fasting.
Anyone else have any experience with this?
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2022.01.25 19:31 livinglifefearless Why We Are So Psychologically Wired To Enjoy Apocalyptic Films That Mirror Our Reality

Why We Are So Psychologically Wired To Enjoy Apocalyptic Films That Mirror Our Reality submitted by livinglifefearless to livinglifefearless [link] [comments]


2022.01.25 19:31 tashaalouxx Hey so I have an Honor 50 and when I'm using the phone the volume slider keeps coming up like the volume button is pressed all the time. I've restarted the phone aswel

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2022.01.25 19:31 Some-Vermicelli7309 Reinforcements? How to find what they are?

Ok I know what they are, and somewhat have an idea what they are used for. Can someone explain it in an at home setting or school setting? My kid who is Kinder is having trouble keeping his hands to himself ( tapping, poking his classmates). His teacher asked me what kind of reinforcements we use at home which I’ll be honest with you it’s mostly his iPad. Losing TV privilege is one too. I don’t normally take his toys away unless he is destroying them (rarely). He is in an autism class so his teacher understand it’s him not properly regulating his behavior. We are trying to find ways that work at home they can use at school if possible. This is all new to me btw, my son was diagnosed beginning of the school year so I’m not familiar with types of disciples for ND children quite yet.
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2022.01.25 19:31 Bhottine Mad Forest (Hyper) done with only bone as a damaging weapon

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2022.01.25 19:31 HRJafael Roll out more barrels? Population boom brings additional liquor sales licenses to Worcester

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2022.01.25 19:31 gungalmao odd flex but ok

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2022.01.25 19:31 ischalkbetter is the left trying to take back the anti-vax title with Kennedy?

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2022.01.25 19:31 LunarFailnaught Rematching AR D Replays

So i’ve seen people in the past talk about why they rematch people who beat their aether raids defense. What is the benefit of rematching players? Does is actually do anything different from doing normal AR Offense attacks? I’ve never understood why people rematch. Thanks!
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2022.01.25 19:31 rideaselle How can I stop the obscene amount of spam calls and texts?

I’ve added my number to the National ‘do not call’ registry but that didn’t do much. I also saw somewhere that you can block your own cell number but that only helped for a few weeks.
Receiving 10+ spam calls and texts a day is getting pretty old, and so is spam bots using my number to call other people. This usually leads to other angry people calling me and asking where I got their number from and why I called them.
Is there any way to combat this? Should I answer every spam call to put my number on a Do Not Call List (assuming they don’t hang up immediately)? Ignore them so they don’t think my number works? Has anyone conquered these demons??
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2022.01.25 19:31 drakelineous [WTS] Elftmann Speed Safety Selector (MD)

Push buttons the safety from Elftmann. Probably the fastest way to manipulate it.
Pics
$30 shipped F&F. Buyer pays G&S fee if going that route.
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2022.01.25 19:31 DaRealNim [Gameboy] Is it necessary to implement the instructions one by one?

[Gameboy] Is it necessary to implement the instructions one by one? Hello everyone. I am currently starting my journey to make my own gameboy emulator. I am currently wondering what the most efficient way to implement the cpu instructions is. I was initially going to go the simple "switch the opcode and consider the 256 cases" way, but looking at the opcode table, they seem to be organized with some logic.

https://preview.redd.it/vi3pcnmsswd81.png?width=1869&format=png&auto=webp&s=638ef1e777d4e89508bfa6143974625232f0e10a
For example we can see that opcodes from 0x40 to 0x7F are load operations, and that half of row 0x4X loads into B and the other half loads into C, while column 0 loads from B, and column 1 loads from C... etc. There are similar patterns for other types of operations, and for 16 bits operations as well.

https://preview.redd.it/v3637g9utwd81.png?width=1820&format=png&auto=webp&s=aba8e58204cab7ca1476d6bce9a85ab03056a6a9
My question is, do you think it would be more code and time efficient to try to implement instructions following that kind of logic, by checking in what range the most significant and least significant 4 bits are? Was that ever made / attempted? Or is it too complicated, and it's better to hardcode the 512 instruction according to each opcode?
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2022.01.25 19:31 StyleShot "Does somebody have a breath mint"

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2022.01.25 19:31 jazzyjff13 Down 50% now. Might as well keep holding right?

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2022.01.25 19:31 AcanthocephalaNew947 I don’t know if we’re broken up or not…

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2022.01.25 19:31 Guitars-guns-girls Vortex issues

One notable issue with vortex optics, their sticker game is weak!
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2022.01.25 19:31 vannaxox at my best self 💗

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2022.01.25 19:31 Chandbn Naughty Riley 🖤

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2022.01.25 19:31 GojoTojo 19/cst/xbox

I basically a bit of everything well maybe except shooters I find them super boring but I play a bunch of rpg, survival, and sandbox games. Right now im getting into elder scrolls online although im pretty bad at it lol but im down to play whatever
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2022.01.25 19:31 Nesquikkk Detoxing from 24mgs cold turkey.

Hey everyone it's been 15 days since I jumped off suboxone and I'm in pure hell with the anxiousness and RLS.
A friend of mine suggest taking a scrap piece of subxone again. Like 0.1 mgs so I can get back to work. Will this reset my withdrawls if I do? I'm so fucking scared of going through the last 2 weeks again, looking for advice and some relief. Thanks in advance.
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2022.01.25 19:31 Chad_Thundermember I regenerate health during beast form... Is it a bug?

Is it a bug? Because I did read in the UESP wiki that when you're in Beast Form, your health regeneration is set to zero. I don't even have any special equipment for it. It just happens.
I do hope all this time I didn't experience any unfair advantages...
So is it a bug?
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2022.01.25 19:31 MedonSirius The difference between two opposite subreddits

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http://andrsosh.ru